Wet harvesting of no-carrier-added 211At from an irradiated 209Bi target for radiopharmaceutical applications

@article{Yordanov2005WetHO,
  title={Wet harvesting of no-carrier-added 211At from an irradiated 209Bi target for radiopharmaceutical applications},
  author={A. Yordanov and O. Pozzi and S. Carlin and G. Akabani and B. Wieland and M. Zalutsky},
  journal={Journal of Radioanalytical and Nuclear Chemistry},
  year={2005},
  volume={262},
  pages={593-599}
}
Astatine-211 is one of the most promising α-emitters for targeted cancer radiotherapy. However, research and clinical trials involving 211At-labeled radiopharmaceuticals have often been impeded due to the irregular and sometimes inconveniently low recovery yields obtained by the currently used dry distillation procedure. Therefore, a wet harvesting procedure isolating 211At from an irradiated 209Bi target was explored. The procedure involves target dissolution in concentrated HNO3 and… Expand
Preparation of no-carrier-added 211At solutions by a simple dry distillation method in the 209Bi(4He, 2n)211At reaction
An overview of targeted alpha therapy