West Nile virus nucleic acid persistence in whole blood months after clearance in plasma: implication for transfusion and transplantation safety.

@article{Lanteri2014WestNV,
  title={West Nile virus nucleic acid persistence in whole blood months after clearance in plasma: implication for transfusion and transplantation safety.},
  author={Marion Christine Lanteri and Tzong-Hae Lee and Li Wen and Zhanna Kaidarova and M. D Serrano Bravo and Nancy E Kiely and Hany T Kamel and Leslie H. H. Tobler and Philip J Norris and Michael P. Busch},
  journal={Transfusion},
  year={2014},
  volume={54 12},
  pages={
          3232-41
        }
}
BACKGROUND Previous reports of West Nile virus (WNV) RNA persistence in blood compartments have raised concerns around the remaining risk of WNV transfusion transmission. This study characterized the dynamics of WNV viremia in blood compartments in a longitudinal cohort of 54 WNV-infected blood donors. STUDY DESIGN AND METHODS Blood samples were collected throughout the year after WNV RNA-positive blood donation (index) and characterized for WNV immunoglobulin (Ig)M and IgG antibodies and for… CONTINUE READING
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