West Nile virus lineage 2 as a cause of zoonotic neurological disease in humans and horses in southern Africa.

@article{Venter2010WestNV,
  title={West Nile virus lineage 2 as a cause of zoonotic neurological disease in humans and horses in southern Africa.},
  author={Marietjie Venter and Robert Swanepoel},
  journal={Vector borne and zoonotic diseases},
  year={2010},
  volume={10 7},
  pages={
          659-64
        }
}
West Nile virus (WNV) is widely distributed in South Africa, but since a few cases of neurological disease have been reported from this region, endemic lineage 2 strains were postulated to be of low virulence. Several cases of nonfatal encephalitis in humans as well as fatal cases in a foal, dog, and ostrich chicks have, however, been associated with lineage 2 WNV in South Africa. The pathogenesis of lineage 2 WNV strains was investigated using mouse neuroinvasive experiments, gene expression… 
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