West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5.


West Nile virus (WNV) is a mosquito-borne flavivirus that causes epidemics of encephalitis and viscerotropic disease worldwide. This virus has spread rapidly and has posed a significant public health threat since the outbreak in New York City in 1999. The interferon (IFN)-mediated antiviral response represents an important component of virus-host… (More)
DOI: 10.1128/JVI.02396-16