West Nile Virus-Induced Activation of Mammalian Target of Rapamycin Complex 1 Supports Viral Growth and Viral Protein Expression

@article{Shives2014WestNV,
  title={West Nile Virus-Induced Activation of Mammalian Target of Rapamycin Complex 1 Supports Viral Growth and Viral Protein Expression},
  author={K. Shives and E. Beatman and Mastooreh Chamanian and Caitlin A O'Brien and J. Hobson-Peters and J. D. Beckham},
  journal={Journal of Virology},
  year={2014},
  volume={88},
  pages={9458 - 9471}
}
ABSTRACT Since its introduction in New York City, NY, in 1999, West Nile virus (WNV) has spread to all 48 contiguous states of the United States and is now the leading cause of epidemic encephalitis in North America. As a member of the family Flaviviridae, WNV is part of a group of clinically important human pathogens, including dengue virus and Japanese encephalitis virus. The members of this family of positive-sense, single-stranded RNA viruses have limited coding capacity and are therefore… Expand
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