Well-Differentiated Fetal Adenocarcinoma of the Lung: Early-Phase Sequential High-Resolution Computed Tomographic Findings

  title={Well-Differentiated Fetal Adenocarcinoma of the Lung: Early-Phase Sequential High-Resolution Computed Tomographic Findings},
  author={Kiyomi Furuya and Kotaro Yasumori and Sadanori Takeo and Noriko Uesugi and Yasuhiro Otsu and Masao Ichiki and Toru Muranaka},
  journal={Journal of Computer Assisted Tomography},
Well-differentiated fetal adenocarcinoma is a rare primary adenocarcinoma originating in the lung. We present an early phase case that was followed up for 2 years with chest roentgens and high-resolution computed tomography. Multicentric origin was suspected in the sequential high-resolution computed tomography study findings. 
A 31-Year-Old Man with Well-differentiated Fetal Adenocarcinoma
This article reports a patient who was found to have a well-differentiated fetal type adenocarcinoma, following left lower lobectomy, believing that the identification of this cancer subtype in patients with lung carcinoma will reduce unnecessary radical treatment methods beyond surgery.
Well differentiated fetal adenocarcinoma of the lung in a 38-year-old woman: dynamic computed tomography findings
This is the first report of dynamic CT findings of WDFA, a rare lung tumor, and although these findings are non-specific, they well reflected the pathological characteristics of this tumor.
Well-differentiated fetal adenocarcinoma of the lung: positron emission tomography features and diagnostic difficulties in frozen section analysis—a case report
A rare case of well-differentiated fetal adenocarcinoma of the lung that was difficult to diagnose based on radiological evaluations including FDG-PET and intraoperatively diagnosed using frozen section analysis is reported.
Fetal adenocarcinoma — a rare variant of lung adenocarcinoma with good prognosis
A case of 32-year-old male, a smoker, who had an incomplete regression of parenchymal consolidations after antibiotic treatment, which led to further diagnostics, and fetal adenocarcinoma was diagnosed, which represents approximately 0.5% of all primary lung neoplasms.
Aspiration cytomorphology of fetal adenocarcinoma of the lung.
Cytomorphologic attributes included small, uniform, round nuclei; morules; and neuroendocrine differentiation in glandular epithelial cells; Immunochemically, all tumors manifested epithelial and neuro endocrine differentiation.


High-resolution CT findings of diffuse bronchioloalveolar carcinoma in 38 patients.
Although these high-resolution CT findings are not specific, the combination of consolidation and nodules and the coexistence of centrilobular nodulesand remote areas of ground-glass attenuation are characteristic of diffuse bronchioloalveolar carcinoma.
Pulmonary blastoma.
Pulmonary blastoma is a mixed tumour with malignant epithelial and connective tissue components with a distinctive resemblance to fetal lung, and it is doubtful whether the tumour has a true blastomatous origin.
Six cases of well-differentiated adenocarcinoma simulating fetal lung tubules in pseudoglandular stage: Comparison with pulmonary blastoma
Six cases of well-differentiated adenocarcinoma resembling fetal lung were studied histologically, immunohistochemically, and ultrastructurally, and compared with three cases of pulmonary blastoma and may be a tumor with one-sided development of pulmonary Blastoma showing only an epithelial component.
Pulmonary blastomas
The idea that histologic class and gross and clinical findings can be of prognostic value in pulmonary blastoma is supported, and the presence of thoracic adenopathy by chest radiography and metastasis at initial presentation were the factors most highly correlated with poor prognosis.
Combined small cell carcinoma with pulmonary blastoma and adenocarcinoma: case report and clonality analysis.
Histological Typing of Lung and Pleural Tumours
The TNM Classification of Malignant Mesothelioma of the Pleura is applied to lung and Pleural Tumours because of the high unclassifiedness of these tumours.
Pulmonary blastoma with argyrophil cells and lacking sarcomatous features (pulmonary endodermal tumor resembling fetal lung).
A tumor of the lung in a 35-year-old woman contained numerous complex, branching tubules resembling the developing fetal lung in its canalicular state, suggesting an endodermal origin for this neoplasm.
Bronchioloalveolar carcinoma: clinical, histopathologic, and radiologic findings.
The single nodular form has a better prognosis than the others but may show false-negative results for malignancy at 2-(fluorine-18) fluoro-2-deoxy-D-glucose positron emission tomography.
p53 and MDM2 immunostaining in pulmonary blastomas and bronchogenic carcinomas.
Pulmonary blastomas. Cancer. 1991;67:2368Y2381
  • Furuya et al J Comput Assist Tomogr & Volume 32, Number
  • 2008