Weighted clustering of called array CGH data.

@article{Wieringen2008WeightedCO,
  title={Weighted clustering of called array CGH data.},
  author={Wessel N van Wieringen and Mark A. van de Wiel and Bauke Ylstra},
  journal={Biostatistics},
  year={2008},
  volume={9 3},
  pages={484-500}
}
Array comparative genomic hybridization (aCGH) is a laboratory technique to measure chromosomal copy number changes. A clear biological interpretation of the measurements is obtained by mapping these onto an ordinal scale with categories loss/normal/gain of a copy. The pattern of gains and losses harbors a level of tumor specificity. Here, we present WECCA (weighted clustering of called aCGH data), a method for weighted clustering of samples on the basis of the ordinal aCGH data. Two… CONTINUE READING

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