Weighted Network-Based Inference of Human MicroRNA-Disease Associations

@article{Jiang2010WeightedNI,
  title={Weighted Network-Based Inference of Human MicroRNA-Disease Associations},
  author={Qinghua Jiang and Yangyang Hao and Guohua Wang and Tianjiao Zhang and Yadong Wang},
  journal={2010 Fifth International Conference on Frontier of Computer Science and Technology},
  year={2010},
  pages={431-435}
}
The identification of disease microRNAs is vital for understanding the pathogenesis of diseases at the molecular level, and is critical for designing specific molecular tools for diagnosis, treatment and prevention. However, one major issue in microRNA studies is the lack of bioinformatics methods to accurately predict microRNA-disease associations. Herein, we proposed an approach to infer microRNA-disease associations based on a weighted network. We tested our method on benchmark dataset… CONTINUE READING

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