Weight-related dosing, timing and monitoring hydrocortisone replacement therapy in patients with adrenal insufficiency.

@article{Mah2004WeightrelatedDT,
  title={Weight-related dosing, timing and monitoring hydrocortisone replacement therapy in patients with adrenal insufficiency.},
  author={Peak Mann Mah and Richard C. Jenkins and Amin Rostami-Hodjegan and John Newell-Price and Anita Doane and Victoria Ibbotson and Geoffrey T. Tucker and Richard J. M. Ross},
  journal={Clinical endocrinology},
  year={2004},
  volume={61 3},
  pages={367-75}
}
OBJECTIVE The objective of this study was to examine the variables determining hydrocortisone (HC) disposition in patients with adrenal insufficiency and to develop practical protocols for individualized prescribing and monitoring of HC treatment. DESIGN AND PATIENTS Serum cortisol profiles were measured in 20 cortisol-insufficient patients (09.00 h cortisol < 50 nmol/l) given oral HC as either a fixed or 'body surface area-adjusted' dose in the fasted or fed state. Endogenous cortisol levels… CONTINUE READING

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View 4 Excerpts
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View 5 Excerpts
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References

Publications referenced by this paper.
Showing 1-10 of 28 references

An assessment of optimal hydrocortisone replacement therapy.

Clinical endocrinology • 1997
View 6 Excerpts
Highly Influenced

Adrenal insufficiency.

Lancet • 2003
View 2 Excerpts

Clinical review 130: Addison's disease 2001.

The Journal of clinical endocrinology and metabolism • 2001

Glucocorticoid therapy. In: Endocrinology

L. Axelrod
2001
View 1 Excerpt

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