Weight loss is associated with improvements in cognitive function among overweight and obese people: A systematic review and meta-analysis

@article{Veronese2017WeightLI,
  title={Weight loss is associated with improvements in cognitive function among overweight and obese people: A systematic review and meta-analysis},
  author={Nicola Veronese and Silvia Facchini and Brendon Stubbs and Claudio Luchini and Marco Solmi and Enzo Manzato and Giuseppe Sergi and Stefania Maggi and Theodore D. Cosco and Luigi Fontana},
  journal={Neuroscience \& Biobehavioral Reviews},
  year={2017},
  volume={72},
  pages={87-94}
}
HIGHLIGHTSIn our meta‐analysis, weight loss was associated with an improvement in attention and memory.Executive function and language improved in longitudinal and RCT studies, respectively.Intentional weight loss should be promoted in obese/overweight people. ABSTRACT Whilst obesity is associated with a higher risk of cognitive impairment, the influence of weight loss on cognitive function in obese/overweight people is equivocal. We conducted a meta‐analysis of randomized controlled trials… 
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References

SHOWING 1-10 OF 61 REFERENCES
Intentional weight loss in overweight and obese individuals and cognitive function: a systematic review and meta‐analysis
  • M. Siervo, R. Arnold, +5 authors B. Stephan
  • Medicine
    Obesity reviews : an official journal of the International Association for the Study of Obesity
  • 2011
TLDR
Weight loss appears to be associated with low‐order improvements in executive/attention functioning and memory in obese but not in overweight individuals.
Effects of Intentional Weight Loss on Physical and Cognitive Function in Middle-Aged and Older Obese Participants: A Pilot Study
TLDR
Weight loss in middle-aged and in older obese participants has a beneficial effect on cognitive and physical function and can significantly affect public health strategies for the prevention of dementia as well as on the clinical management of obesity.
Effect of weight loss, exercise, or both on cognition and quality of life in obese older adults.
TLDR
Weight loss and exercise each improve cognition and HRQOL, but their combination may provide benefits similar to exercise alone.
Caloric Restriction in Older Adults—Differential Effects of Weight Loss and Reduced Weight on Brain Structure and Function
TLDR
Improved recognition memory was found, paralleled by increased gray matter volume in inferior frontal gyrus and hippocampus, and augmented hippocampal resting‐state functional connectivity to parietal areas, in the CR group.
The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies.
TLDR
A systematic review and meta-analysis of the up-to-date current literature suggests a positive association between obesity in mid-life and later dementia but the opposite in late life.
Diet-Induced Weight Loss Alters Functional Brain Responses during an Episodic Memory Task
TLDR
Investigating whether a reduction in body weight by dietary interventions could improve episodic memory performance and alter associated functional brain responses in overweight and obese women found that diet-induced weight loss, associated with decreased levels of plasma FFA, improves episodicMemory linked to increased hippocampal activity.
Corrigenda: Corrigendum to 'The risk of overweight/obesity in mid-life and late life for the development of dementia: a systematic review and meta-analysis of longitudinal studies'.
TLDR
A systematic review and meta-analysis of the up-to-date current literature suggests a positive association between obesity in mid-life and later dementia but the opposite in late life.
Cognitive effects of a long-term weight reducing diet
TLDR
Control long-term caloric restriction significantly slowed simple reaction time but did not diminish sustained attention, motor performance or immediate memory, and sustained attention and immediate memory were not impaired with long- term caloric restriction.
Cognitive effects of ketogenic weight-reducing diets.
  • R. Wing, J. Vazquez, C. Ryan
  • Medicine
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity
  • 1995
TLDR
Performance on the trail making task, a neuropsychological test that requires higher order mental processing and flexibility, was adversely affected by the ketogenic diet and a worsening in performance was observed primarily between baseline and week one of theketogenic diet.
Optimal body weight for health and longevity: bridging basic, clinical, and population research
TLDR
From a clinical and public health point of view, maintaining a healthy weight through diet and physical activity should remain the cornerstone in the prevention of chronic diseases and the promotion of healthy aging.
...
1
2
3
4
5
...