Weight loss in neurodegenerative disorders

  title={Weight loss in neurodegenerative disorders},
  author={N. Ahmad Aziz and Marjolein A. Marck and Hanno Pijl and Marcel G M Olde Rikkert and Bastiaan R. Bloem and Raymund A. C. Roos},
  journal={Journal of Neurology},
Unintended weight loss frequently complicates the course of many neurodegenerative disorders and can contribute substantially to both morbidity and mortality. This will be illustrated here by reviewing the characteristics of unintended weight loss in the three major neurodegenerative disorders: Alzheimer’s disease, Parkinson’s disease and Huntington’s disease. A common denominator of weight loss in these neurodegenerative disorders is its typically complex pathophysiology. Timely recognition of… 
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Attention must be paid as well to motor symptoms to prevent or reverse weight loss in PD patients, and to enhance glucose metabolism resulting in enhanced energy expenditure.
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