• Corpus ID: 10775595

Weight gain Rashes Depression Fatigue Irritability Tachycardia Insomnia Vision Problems Hearing Loss Heart palpitations Breathing difficulties Anxiety attacks Slurred Speech Loss of taste Tinnitus Vertigo Memory loss Joint Pain

@inproceedings{Barua2006WeightGR,
  title={Weight gain Rashes Depression Fatigue Irritability Tachycardia Insomnia Vision Problems Hearing Loss Heart palpitations Breathing difficulties Anxiety attacks Slurred Speech Loss of taste Tinnitus Vertigo Memory loss Joint Pain},
  author={Debashis Barua},
  year={2006}
}
Aspartame is the most widely used artificial sweetener & has captured 50% of the world market since it was introduced in 1981. It is available in 90 countries over the world, in more than 5000 products. The largest consumer is the United States of America ( 54% of adult Americans ). In India it is still being used only as a table-top sweetener ( e.g. Equal, SugarFree & Sweetex-Gold ), the users being limited to a part of the diabetic population & the affluent diet-conscious population, mostly… 

References

SHOWING 1-10 OF 48 REFERENCES

Aspartame: clinical update.

Since the introduction of aspartame into the American food supply in 1981, it has grown to become the most widely used and accepted artificial sweetener. However, recent published and unpublished

Aspartame-induced lobular panniculitis.

Tryptophan depletion causes a rapid lowering of mood in normal males

Although the mood-lowering effect was not as great as that seen in depressed patients, the results suggest that low brain 5HT might be one factor precipitating depression in some patients.

Glutamate-type hypothalamic-pituitary syndrome in mice treated with aspartate or cysteate in infancy

It is demonstrated that the same hypothalamic lesion and syndrome of neuroendocrine manifestations occurs following treatment of infant mice with either of two other neuroexcitatory amino acids (L-cysteic or L-aspartic acids) which destroy arcuate neurons but not from a structurally related amino acid (DL-α-aminoadipic acid) which lacks neuro excitatory properties and spares arcsuate neurons.

Excitatory amino acids as a final common pathway for neurologic disorders.

In many neurologic disorders, injury to neurons may be caused at least in part by overstimulation of receptors for excitatory amino acids, including glutamate and aspartate. These neurologic

Aspartame Consumption in Normal Individuals and Carriers for Phenylketonuria

Aspartame, a widely used sweetener, was studied in 53 adults, 28 of whom were carriers for phenylketonuria (PKU), and blood phenylalanine levels were greater than 10 mg/dl in 12% of carriers for PKU and in 5% of the normal controls.

Aspartame-induced granulomatous panniculitis.

  • N. Novick
  • Medicine
    Annals of internal medicine
  • 1985
Excerpt The Low-Calorie Artificial Sweetener, aspartame (NutraSweet; G.D. Searle & Co., Skokie, Illinois), a synthetic combination of aspartic acid and the methyl ester of phenylalanine, is current...

Brain Damage in Infant Mice following Oral Intake of Glutamate, Aspartate or Cysteine

It is found that a similar process of acute neuronal necrosis occurs in several regions of the infant mouse brain after subcutaneous treatment with MSG, and that animals treated with high doses in infancy tend to manifest obesity and neuroendocrine disturbances as adults.

Biochemical and neuropsychological effects of elevated plasma phenylalanine in patients with treated phenylketonuria. A model for the study of phenylalanine and brain function in man.

Ten older, treated, phenylketonuric patients using a triple-blind, multiple trials, crossover design are studied, finding an inverse relationship between plasma phenylalanine and urine dopamine excretion and one mechanism may involve impaired biogenic amine synthesis.