Weight change, genetics and antiepileptic drugs
@article{Chukwu2014WeightCG, title={Weight change, genetics and antiepileptic drugs}, author={J. Chukwu and N. Delanty and D. Webb and G. Cavalleri}, journal={Expert Review of Clinical Pharmacology}, year={2014}, volume={7}, pages={43 - 51} }
Weight gain caused by antiepileptic drugs (AEDs) constitutes a serious problem in the management of people with epilepsy. AEDs associated with weight gain include sodium valproate, pregabalin and vigabatrin. Excessive weight gain can lead to non-compliance with treatment and to an exacerbation of obesity-related conditions. The mechanisms by which AEDs cause weight gain are not fully understood. It is likely that weight change induced by some AEDs has a genetic underpinning, and recent… CONTINUE READING
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