Wegener's granulomatosis. Clinical features and outcome in 13 patients.

  title={Wegener's granulomatosis. Clinical features and outcome in 13 patients.},
  author={Steven L Brandwein and John Esdaile and Deborah Danoff and Hyman Tannenbaum},
  journal={Archives of internal medicine},
  volume={143 3},
Thirteen patients with Wegener's granulomatosis were seen over 10.5 years. The clinical features resembled those in previously reported series, except for the increased frequency of inflammatory arthritis, which was a prominent early feature in ten patients (77%). Four (31%) of the 13 had fulminant vasculitis and died before receiving an adequate course of cytotoxic drug therapy. Two of these four had a pulmonary-renal syndrome that mimicked Goodpasture's syndrome. All of the remaining nine… CONTINUE READING


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