Wegener's granulomatosis: clinical manifestations, differential diagnosis, and management of ocular and systemic disease.

@article{Tarabishy2010WegenersGC,
  title={Wegener's granulomatosis: clinical manifestations, differential diagnosis, and management of ocular and systemic disease.},
  author={Ahmad Bakir Tarabishy and M Schulte and George Nick Papaliodis and Gary S. Hoffman},
  journal={Survey of ophthalmology},
  year={2010},
  volume={55 5},
  pages={
          429-44
        }
}
Wegener's granulomatosis (WG) is a systemic inflammatory disease whose histopathologic features often include necrosis, granuloma formation, and vasculitis of small-to-medium-sized vessels. WG involves many interrelated pathogenic pathways that are genetic, cell-mediated, neutrophil-mediated, humoral, and environmental. WG most commonly involves the upper respiratory tract, lungs, and kidneys, but has been reported to affect almost any organ. Ophthalmologic involvement is an important cause of… CONTINUE READING
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