Wedge-shaped medullary lesions in multiple sclerosis

  title={Wedge-shaped medullary lesions in multiple sclerosis},
  author={Wei Qiu and Sonja Raven and Jingshan Wu and William M Carroll and Frank L Mastaglia and Allan G. Kermode},
  journal={Journal of the Neurological Sciences},
Spinal cord involvement in multiple sclerosis: A correlative MRI and high-resolution HLA-DRB1 genotyping study
Mystery of Chronic Cerebrospinal Venous Insufficiency: Identical Venographic and Ultrasound Findings in Patients with MS and Controls
The authors used high-resolution sonography to image neck vessels in 32 patients with MS and controls using the Zamboni criteria to find no differences were detected between patients and controls by using these criteria and that normal physiologic narrowing was very common in the internal jugular veins in controls.
Internal jugular vein morphology and hemodynamics in patients with multiple sclerosis.
Hemodynamic abnormalities and morphological changes involving the internal jugular vein are strongly associated with MS and can be demonstrated by a non-invasive, cost effective Doppler ultrasound criteria.
Multiple sclerosis: cerebral circulation time.
The results suggest that contrast-enhanced US with CCT assessment may have a role in the evaluation of cerebral blood flow in patients with MS and that a vascular impairment could be associated with MS.
Assessing lesion morphology in MS: Why does this matter?


The ovoid lesion: a new MR observation in patients with multiple sclerosis.
The frequency of oval-shaped, high-signal-intensity lesions oriented perpendicular to the anteroposterior axis of the brain on abnormal, axial T2-weighted MR brain scans in 59 patients with clinically documented multiple sclerosis correlates with the neuropathologic description of demyelination in multiple sclerosis.
Topological characteristics of brainstem lesions in clinically definite and clinically probable cases of multiple sclerosis: an MRI-study
If there is a predilection for the outer or inner surfaces of the brainstem, such lesions can be considered an additional typical feature of multiple sclerosis and can be more reliably weighted as paraclinical evidence for a definite diagnosis.
Breakdown of the blood-brain barrier precedes symptoms and other MRI signs of new lesions in multiple sclerosis. Pathogenetic and clinical implications.
From an extensive serial magnetic resonance imaging (MRI) study in multiple sclerosis (MS) we have identified 4 cases in which disruption of the blood-brain barrier, as detected by gadolinium-DTPA
Medial medullary syndrome. Report of 18 new patients and a review of the literature.
It is illustrated that MMS is most often manifested as benign hemisensorimotor stroke frequently associated with tingling sensation and impaired deep sensation, which should be much more common than MMS with poor prognosis.
MRI characteristics of atypical idiopathic inflammatory demyelinating lesions of the brain
It is suggested that IIDLs reported as atypical in the literature can be segregated into several distinct subtypes based on their MRI appearance, which may be useful for the differential diagnosis and for a future classification.
Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria”
New evidence and consensus now strengthen the role of these criteria in the multiple sclerosis diagnostic workup to demonstrate dissemination of lesions in time, to clarify the use of spinal cord lesions, and to simplify diagnosis of primary progressive disease.
THE PRESENT work is an attempt to define the topographic distribution of plaques in the spinal cord in multiple sclerosis, thus contributing to the solution of the old and important question of the
Clinical and MRI study of brain stem and cerebellar involvement in Japanese patients with multiple sclerosis
The low frequency of the cerebellar MRI lesions in these patients is in sharp contrast with the figures reported for white patients with multiple sclerosis, suggesting racial and genetic differences may have an influence on the susceptibility of each part of the CNS to demyelination in multiple sclerosis.
Chronic cerebrospinal venous insufficiency in patients with multiple sclerosis
CDMS is strongly associated with CCSVI, a scenario that has not previously been described, characterised by abnormal venous haemodynamics determined by extracranial multiple venous strictures of unknown origin.
The neuropathology of multiple sclerosis.
The pathology of multiple sclerosis is reviewed in an attempt to allow the reader to better understand the pathogenesis of the lesions.