Weaving a tangled web: the interconnected cytoskeleton


NATURE CELL BIOLOGY | VOL 1 | SEPTEMBER 1999 | cellbio.nature.com E121 region, which contains four hydrophobic heptads, may form a four-stranded coiledcoil in combination with four heptads of each light chain. It is not obvious that, with the light chains bound to the heavy chains, the extreme C terminus of the heavy chain would be exposed, although KLC–KHC complexes clearly undergo the folding reaction. The tip of the kinesin tail remains clouded in mystery, and an important challenge for the future will be to understand how its structure and dynamics combine to regulate kinesin-driven motility. h Robert Cross is at the Molecular Motors Group, Marie Curie Research Institute, The Chart, Oxted, Surrey RH8 0TL, UK. Jonathan Scholey is in the Section of Molecular and Cellular Biology, University of California, Davis, California 95616, USA. e-mail: jmscholey@ucdavis.edu

DOI: 10.1038/12950


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@article{Klymkowsky1999WeavingAT, title={Weaving a tangled web: the interconnected cytoskeleton}, author={Michael W Klymkowsky}, journal={Nature Cell Biology}, year={1999}, volume={1}, pages={E121-E123} }