Weakly acidic reflux in patients with chronic unexplained cough during 24 hour pressure, pH, and impedance monitoring.

@article{Sifrim2005WeaklyAR,
  title={Weakly acidic reflux in patients with chronic unexplained cough during 24 hour pressure, pH, and impedance monitoring.},
  author={Daniel A Sifrim and Lieven Joseph Dupont and Kathleen Blondeau and Xi Zhang and Jan Tack and Jozef Janssens},
  journal={Gut},
  year={2005},
  volume={54 4},
  pages={449-54}
}
BACKGROUND AND AIMS Acid gastro-oesophageal reflux is one of the most important causes of chronic cough. The response to acid suppression in these patients is not as good as in patients with heartburn but improvement with antireflux surgery has been reported, suggesting the involvement of a non-acidic gastric component in the refluxate. Less acidic reflux may produce symptoms such as regurgitation or chest pain. We investigated whether chronic cough might be associated with weakly acidic reflux… CONTINUE READING

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