Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux

@article{Yoshida1995WeakenedCS,
  title={Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux},
  author={Ken-ichi Yoshida and Junich Hirokawa and Seiichi Tagami and Yoshiyuki Kawakami and Yoshishige Urata and Dr. T. Kondo},
  journal={Diabetologia},
  year={1995},
  volume={38},
  pages={201-210}
}
Glutathione functions to scavenge oxidants or xenobiotics by covalently binding them and transporting the resulting metabolites through an adenosine 5′-triphosphate-dependent transport system. It has been reported that the intracellular concentration of glutathione decreases in diabetes mellitus. In order to elucidate the physiological significance and the regulation of anti-oxidants in diabetic patients, changes in the activity of the glutathione-synthesizing enzyme, γ-glutamylcysteine… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 91 CITATIONS, ESTIMATED 39% COVERAGE

235 Citations

01020'95'00'06'12'18
Citations per Year
Semantic Scholar estimates that this publication has 235 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Similar Papers

Loading similar papers…