Weak effect of metal type and ica genes on staphylococcal infection of titanium and stainless steel implants.

@article{Hudetz2008WeakEO,
  title={Weak effect of metal type and ica genes on staphylococcal infection of titanium and stainless steel implants.},
  author={Damir Hudetz and S Ursic Hudetz and Llinos G. Harris and Reto Luginbuehl and Niklaus F. Friederich and R{\'e}gine Landmann},
  journal={Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases},
  year={2008},
  volume={14 12},
  pages={1135-45}
}
Currently, ica is considered to be the major operon responsible for staphylococcal biofilm. The effect of biofilm on susceptibility to staphylococcal infection of different implant materials in vivo is unclear. The interaction of ica-positive (wild-type (WT)) and ica-negative (ica(-)) Staphylococcus aureus and Staphylococcus epidermidis strains with titanium and both smooth and rough stainless steel surfaces was studied by scanning electron microscopy in vitro and in a mouse tissue cage model… CONTINUE READING