Weak acid effects and fluoride inhibition of glycolysis by Streptococcus mutans GS-5.

@article{Belli1995WeakAE,
  title={Weak acid effects and fluoride inhibition of glycolysis by Streptococcus mutans GS-5.},
  author={W A Belli and Donald Buckley and Robert E. Marquis},
  journal={Canadian journal of microbiology},
  year={1995},
  volume={41 9},
  pages={785-91}
}
Fluoride and a variety of other weak acids acted to reduce reversibily the acid tolerance of glycolysis by intact cells of Streptococcus mutans GS-5 as shown by higher final pH values in acid-drop experiments with glucose in excess. The order of effectiveness was fluoride > indomethacin > ibuprofen > ketoprofen > salicylate > sorbate > cinnamate > p-hydroxybenzoate > benzoate > ascorbate. Only fluoride also acted as an inhibitor of the glycolytic enzyme enolase. However, enolase in… CONTINUE READING

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