We should strive for optimal hemodialysis: a criticism of the hemodialysis adequacy concept.

@article{Twardowski2003WeSS,
  title={We should strive for optimal hemodialysis: a criticism of the hemodialysis adequacy concept.},
  author={Zbylut J Twardowski},
  journal={Hemodialysis international. International Symposium on Home Hemodialysis},
  year={2003},
  volume={7 1},
  pages={5-16}
}
Adequacy of hemodialysis is frequently equated with Kt/V(urea) , the amount of urea clearance (K) multiplied by time (t) and divided by urea distribution volume (V). Several formulas have been developed to calculate Kt/V(urea) from the pre- and post-dialysis urea concentrations. In three-times-weekly hemodialysis, a single pool (spKt/V(urea)) value of 1.3 per treatment is commonly considered to indicate adequate therapy. Despite providing the recommended spKt/V(urea) of 1.3 per treatment, short… CONTINUE READING