Ways to Correct Indications for Surgical Treatment of Atherosclerotic Descending Aortic Aneurysms

  title={Ways to Correct Indications for Surgical Treatment of Atherosclerotic Descending Aortic Aneurysms},
  author={Vladimir Petrovich Krylov and N A Manak and Valentina Nikolaevna Gayduk and Nadezhda Vladimirovna Mankevich and Leonid Ivanovich Reut},
Recent studies suggest that the development of atherosclerotic descending aortic aneurysms (DAA) is a complicated process, which occurs due to a polymorphic nature of aortic wall abnormalities. They overlap and contribute to a wide variety of clinical manifestations. The inflammatory process may be the main reason for a rapid growth and rupture of the aneurysm. It also involves a mechanism of complex adhesion comprising of acute-phase proteins to low-density lipoproteins (LDLPs) as… Expand
Long-Term Results (Seven and More Years) of Sparing Treatment of Subjects with Descending Aortic Aneurysms
It seems like medical treatment is more consistent with etiopathogenesis of the disease compared to surgery during the stabilization period, and it is symptomatic that the aneurysm rupture rate was not always affected by operative treatment. Expand


Atherosclerotic Descending Aortic Aneurysms. Pros and Cons of Surgery
An argumentative and sparing medical-and-surgical approach to treatment based on a more in-depth understanding of the etiopathogenesis of the disease whereas surgery would remain of prime importance when appropriate is proposed. Expand
Can We Change a Look at Atherosclerotic Aortic Aneurism Treatment
It is suggested that the odds ratio (OR) of survival when using attenuated therapeutic approach to treating atherosclerotic aneurisms is 2.6-fold higher compared to conventional surgical approach. Expand
Cystic medial necrosis: pathological findings and clinical implications.
  • S. Yuan, H. Jing
  • Medicine
  • Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular
  • 2011
The aim of the present article is to provide a comprehensive overview of the CMN lesion in terms of pathologic features, clinical implications and etiologies based on molecular research results. Expand
What Is New in Dilatation of the Ascending Aorta?: Review of Current Literature and Practical Advice for the Cardiologist
A 61-year-old woman presented with atypical chest complaints. Her sister and brother suffered from type A aortic dissection at 47 and 39 years of age, respectively.1 The diameter of the ascendingExpand
Rupture in small abdominal aortic aneurysms.
Patients who are at good risk with small AAA (between 4 and 5 cm) should be considered for elective aneurysm resection, for unclear reasons, obstructive lung disease and diabetes are associated with a significantly greater risk for rupture of small AAA. Expand
Angiogenesis in abdominal aortic aneurysms.
It is demonstrated that abdominal aortic aneurysms are associated with a marked angiogenic response, which is related to the degree of inflammation within the aortIC wall, and it is hypothesised that anti-angiogenic agents may play a role in the medical management of aorto-aneurysmal disease. Expand
Monitoring the biological activity of abdominal aortic aneurysms Beyond Ultrasound
Abdominal aortic aneurysms (AAAs) are an important cause of morbidity and, when ruptured, are associated with >80% mortality. Current management decisions are based on assessment of aneurysm diameterExpand
From Vulnerable Plaque to Vulnerable Patient
Atherosclerotic cardiovascular disease results in millions of sudden deaths annually, and coronary artery disease accounts for the majority of this toll. Despite major advances in the treatment ofExpand
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.
The term "vulnerable patient" may be more appropriate and is proposed now for the identification of subjects with high likelihood of developing cardiac events in the near future and a quantitative method for cumulative risk assessment of vulnerable patients needs to be developed. Expand
Heterogeneity of Tensile Strength and Matrix Metalloproteinase Activity in the Wall of Abdominal Aortic Aneurysms
Localized “hot spots” of MMP hyperactivity could lead to focal weakening of the aneurysm wall and rupture at relatively low levels of intraluminal pressure, suggesting that tensile strength of the sac is just as important as intrasac tension in determining the risk of rupture. Expand