Water-soluble dietary fibers and cardiovascular disease

  title={Water-soluble dietary fibers and cardiovascular disease},
  author={Elke Theuwissen and Ronald P. Mensink},
  journal={Physiology \& Behavior},
Lipid Lowering with Soluble Dietary Fiber
Findings include that consumption of water-soluble, viscous-forming fibers can reduce total and low-density lipoprotein cholesterol levels by about 5–10 %; and medium to high molecular weight fibers are more effective in reducing lipid levels.
Effects of soluble dietary fiber on low-density lipoprotein cholesterol and coronary heart disease risk
  • L. Bazzano
  • Medicine
    Current atherosclerosis reports
  • 2008
These studies, along with recent analyses of ongoing prospective cohort studies, have provided new insights into the probable protective role of dietary fiber in the development of coronary heart disease and other cardiovascular diseases.
Influence of food components on lipid metabolism: scenarios and perspective on the control and prevention of dyslipidemias
Diet is an important tool for the prevention and control of cardiovascular diseases, and should be taken into account as a whole, i.e., not only the food components that modulate plasma concentrations of lipoproteins, but also the diet content of macro nutrients and micronutrients should be considered.
Dietary Fiber and Hyperlipidemia and Cardiovascular Disease
In this chapter, emphasis is placed on the use of dietary patterns to reduce the risk of CVD, as well as the modulation of intestinal microbiota by the dietary fiber.
Mechanisms underlying the cholesterol-lowering properties of soluble dietary fibre polysaccharides.
Three potential physicochemical mechanisms are proposed together with suggestions for in vitro experiments to test them and the nature of interactions between bile salt micelles and SDF that lead to incomplete BS re-absorption are poorly defined.
The role of soluble fiber intake in patients under highly effective lipid-lowering therapy
Among subjects treated with highly effective lipid-lowering therapy, the intake of 25 g of fibers added favorable effects, mainly by reducing phytosterolemia, and additional benefits include improvement in blood glucose and anthropometric parameters.
Therapeutic effects of soluble dietary fiber consumption on type 2 diabetes mellitus.
It is suggested that increased and regular consumption of soluble DF led to significant improvements in blood glucose levels, insulin resistance and metabolic profiles, without improving the secretory function of the islets of Langerhans, over a short-term intervention period in patients with DM2.
Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type
Both Flax drink and Flax bread resulted in decreased plasma total and LDL-cholesterol and increased fat excretion, but the food matrix and/or processing may be of importance.
Role of naturally-occurring plant sterols on intestinal cholesterol absorption and plasmatic levels
Recent studies show that phytosterols present in natural food matrices are also effective and could be an important component of cardioprotective dietary patterns such as the Mediterranean diet.
Insoluble Carob Fiber Rich in Polyphenols Lowers Total and LDL Cholesterol in Hypercholesterolemic Sujects
The consumption of fiber very rich in insoluble polyphenols shows beneficial effects on human blood lipid profile and may be effective in prevention and treatment of hyperlipemia.


Dietary fibre, complex carbohydrate and coronary artery disease.
  • J. Anderson
  • Medicine
    The Canadian journal of cardiology
  • 1995
Clinical trials and epidemiologic data suggest that the intake of complex carbohydrate and dietary fibre is associated in an inverse manner to risk for coronary artery disease (CAD), and intake of dietary fibre and complex carbohydrate appear to have a protective role for CAD.
Cholesterol-lowering effects of dietary fiber: a meta-analysis.
A meta-analysis of 67 controlled trials was performed to quantify the cholesterol-lowering effect of major dietary fibers, finding that increasing soluble fiber can make only a small contribution to dietary therapy to lower cholesterol.
Cholesterol-lowering Effects of Dietary Fiber
There has been increasing reports concerning several physiological responses, such as lowering of plasma cholesterol levels, modification of glycemic response, improving large bowel function, and
Beta-glucan incorporated into a fruit drink effectively lowers serum LDL-cholesterol concentrations.
A reduced cholesterol absorption contributes to the cholesterol-lowering effect of beta-glucan without affecting plasma concentrations of lipid-soluble antioxidants.
Lipids Significantly Reduced by Diets Containing Barley in Moderately Hypercholesterolemic Men
Increasing soluble fiber through consumption of barley in a healthy diet can reduce cardiovascular risk factors.
The effects of concentrated barley β-glucan on blood lipids in a population of hypercholesterolaemic men and women
Concentrated BBG significantly improves LDL-C and total cholesterol among moderately dyslipidaemic subjects and food products containing concentrated BBG should be considered an effective option for improving blood lipids.
Comparison of the effects of oat bran and low-fiber wheat on serum lipoprotein levels and blood pressure.
It is concluded that oat bran has little cholesterol-lowering effect and that high-fiber and low- fiber dietary grain supplements reduce serum cholesterol levels about equally, probably because they replace dietary fats.
Soluble fiber and serum lipids: a literature review.
Oat-bran intake selectively lowers serum low-density lipoprotein cholesterol concentrations of hypercholesterolemic men.
Palatable and inexpensive high-fiber foods such as oat bran may have a role in the treatment of certain patients with hypercholesterolemia.
Oat-derived β-Glucan Significantly Improves HDLC and Diminishes LDLC and Non-HDL Cholesterol in Overweight Individuals With Mild Hypercholesterolemia
Six grams of β-glucan from oats added to the AHA Step II diet and moderate physical activity improved lipid profile and caused a decrease in weight and, thus, reduced the risk of cardiovascular events in overweight male individuals with mild to moderate hypercholesterolemia.