Water-soluble and biocompatible sono/photosensitizer nanoparticles for enhanced cancer therapy.

@article{Meng2010WatersolubleAB,
  title={Water-soluble and biocompatible sono/photosensitizer nanoparticles for enhanced cancer therapy.},
  author={Yongde Meng and Chunpu Zou and Ragupathy Madiyalakan and Thomas Woo and Min Kyoo Kang Rui Huang and Xiaoyan Yang and Eric Swanson and Jie Chen and James Z. Xing},
  journal={Nanomedicine},
  year={2010},
  volume={5 10},
  pages={1559-69}
}
AIMS Most sono/photosensitizers of cancer sonodynamic/photodynamic therapy (SDT/PDT), such as hypocrellin SL052, are water-insoluble, therefore restricting their clinical applications. In this article, we present a water-soluble nanocarrier to load the SDT/PDT sensitizer SL052 with improved pharmacokinetics and therapeutic efficacy. MATERIALS & METHODS Nanoclusters of polyvinylpyrrolidones with SL052 formed water-soluble nanoparticles (SL052-NPs) while retaining the chemical structure of… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 16 references

Sonodynamic therapy

Feril Tachibana K, Y Ikeda-Dantsuji
2008

anoscale materials development - a food industry perspective

MA NSanguansriP.Augustin
Trends Food Sci. Technol • 2006

Gasn AR. PedrazJL: Micro and nano drug delivery systems

G Orive, RM Hernndez
Cancer 6 Ther • 2005

An approach to enhancing the phototoxicity of a novel hypocrellin congener to MGCB 03 cells

HY Yang, T Wu, +4 authors Y Yoshioka
2001

ZY: An approach to enhancing the phototoxicity of a novel hypocrellin congener to MGCB03 cells

HY Yang, WG Zhang, LP Ma, SW Wang, Zhang
Dyes Pigm • 2001

Similar Papers

Loading similar papers…