Corpus ID: 8487921

Water-retention effect of suberogorgin was due to secretion of antidiuretic hormone in rat.

@article{Peng1999WaterretentionEO,
  title={Water-retention effect of suberogorgin was due to secretion of antidiuretic hormone in rat.},
  author={W. Peng},
  journal={Zhongguo yao li xue bao = Acta pharmacologica Sinica},
  year={1999},
  volume={20 6},
  pages={
          559-62
        }
}
  • W. Peng
  • Published 1999
  • Chemistry, Medicine
  • Zhongguo yao li xue bao = Acta pharmacologica Sinica
AIM To study the mechanism of antidiuretic effect of suberogorgin (Sub). METHODS Conscious rat was given i.g. Sub 3.16 mg.kg-1 20 min after water-loaded treatment and then urine was collected in metabolic cage. Ion excretion was determined in atomic emission spectrometry. Urinary prostaglandin E (PGE), plasma PGE, antidiuretic hormone (ADH), and aldosterone were measured with RIA. Sub vs pituitrin or DOCA effects were carried out in hypophysectomized or adrenalectomized rats. RESULTS The… Expand