Water immersion wrinkling

  title={Water immersion
  author={Einar P. V. Wilder-Smith},
  journal={Clinical Autonomic Research},
  • E. Wilder-Smith
  • Published 1 April 2004
  • Engineering
  • Clinical Autonomic Research
Abstract.Water immersion skin wrinkling is an indicator of limb sympathetic function. Routine clinical usage of this enigmatic phenomenon is hampered by poor endpoint quantification, which involves counting skin folds. The recent discovery of the importance of vasoconstriction in immersion wrinkling suggests digital blood flow or volume changes as better endpoints. Water probably initiates the wrinkling process by altering epidermal electrolyte homeostasis as it diffuses into the porous skin of… 

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