Water deprivation increases Fos immunoreactivity in PVN autonomic neurons with projections to the spinal cord and rostral ventrolateral medulla.

@article{Stocker2004WaterDI,
  title={Water deprivation increases Fos immunoreactivity in PVN autonomic neurons with projections to the spinal cord and rostral ventrolateral medulla.},
  author={Sean D Stocker and J Thomas Cunningham and Glenn M Toney},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2004},
  volume={287 5},
  pages={R1172-83}
}
The present study sought to determine whether water deprivation increases Fos immunoreactivity, a neuronal marker related to synaptic activation, in sympathetic-regulatory neurons of the hypothalamic paraventricular nucleus (PVN). Fluorogold (4%, 50 nl) and cholera toxin subunit B (0.25%, 20-30 nl) were microinjected into the spinal cord (T1-T3) and rostral ventrolateral medulla (RVLM), respectively. Rats were then deprived of water but not food for 48 h. Water deprivation significantly… CONTINUE READING

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Discharge properties and osmotic responsiveness of hypothalamic PVN neurons projecting to the ventrolateral medulla and spinal cord (Abstract)

  • QH Chen, GM Toney
  • FASEB J
  • 2000
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