Water content measured by proton-deuteron exchange NMR predicts bone mineral density and mechanical properties.

@article{FernndezSeara2003WaterCM,
  title={Water content measured by proton-deuteron exchange NMR predicts bone mineral density and mechanical properties.},
  author={Mar{\'i}a A. Fern{\'a}ndez-Seara and Suzanne L. Wehrli and Masaya Takahashi and Felix W. Wehrli},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2003},
  volume={19 2},
  pages={
          289-96
        }
}
UNLABELLED NMR was used to measure matrix water content in normal and hypomineralized cortical bone. Water content showed an inverse relationship with mineral content, suggesting it could serve as a surrogate measure for the bone's degree of mineralization. INTRODUCTION So far, true bone mineral density (DMB; degree of mineralization of bone) can not be measured nondestructively. MATERIALS AND METHODS Here, a new technique combining 1H nuclear magnetic resonance (NMR) spectroscopy and… CONTINUE READING
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