Water channel properties of major intrinsic protein of lens.

@article{Mulders1995WaterCP,
  title={Water channel properties of major intrinsic protein of lens.},
  author={Sabine M. Mulders and Gregory M. Preston and Peter M T Deen and William B Guggino and C. H. van Os and Peter Agre},
  journal={The Journal of biological chemistry},
  year={1995},
  volume={270 15},
  pages={9010-16}
}
The functions of major intrinsic protein (MIP) of lens are still unresolved; however the sequence homology with channel-forming integral membrane protein (CHIP) and other Aquaporins suggests that MIP is a water channel. Immunolocalizations confirmed that Xenopus oocytes injected with bovine MIP cRNA express the protein and target it to the plasma membrane… CONTINUE READING