Water and solute balance in rats during 10 h water deprivation and rehydration.

@article{Schoorlemmer1993WaterAS,
  title={Water and solute balance in rats during 10 h water deprivation and rehydration.},
  author={Guus H. M. Schoorlemmer and Mark D Evered},
  journal={Canadian journal of physiology and pharmacology},
  year={1993},
  volume={71 5-6},
  pages={379-86}
}
Rats with bladder and venous cannulas were deprived of water from midnight (00:00) to 10:00. Water deprivation reduced food intake within 2 h, reducing the amount of water sequestered in the gut and the solute load to the tissues. There was little change in either urinary water loss or osmolality, but water-deprived rats excreted more Na+, K+, and Cl- than food-matched controls. The change in solute balance helped preserve osmolality and cell volume at the expense of extracellular fluid volume… CONTINUE READING
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