Water‐immersion wrinkling is due to vasoconstriction

  title={Water‐immersion wrinkling is due to vasoconstriction},
  author={Einar P. V. Wilder-Smith and Adeline W L Chow},
  journal={Muscle \& Nerve},
The underlying mechanism of the water‐immersion skin wrinkling test, which is used as a test of sympathetic nerve function, remains elusive. We investigated changes of blood circulation in the hand occurring with water‐immersion wrinkling by measuring the velocity of ulnar and digital artery blood flow, and of digit skin blood flow, in healthy subjects before and during wrinkling. Wrinkling was accompanied by significant reduction in blood flow velocity in all vessels, with a maximum in digital… Expand
Water immersion and EMLA cause similar digit skin wrinkling and vasoconstriction.
The EMLA cream patch test may develop into a useful screening test for hand sympathetic vasoconstrictor function and further support that water immersion skin wrinkling is mediated by vasconstriction. Expand
Water immersion wrinkling
The physiology of water immersion wrinkling is discussed and its potential as an indicator of limb sympathetic dysfunction is explored and digital blood flow or volume changes are suggested as better endpoints. Expand
Paradoxical response to water immersion in replanted fingers
The paradoxical cutaneous vasodilatation and absence of wrinkling in the denervated fingers suggests that sympathetic innervation is important in water-immersion skin wrinkling. Expand
EMLA and water immersion cause similar vasodilatation in replanted fingers.
EMLA and water immersion both cause vasodilatation and no skin wrinkling in replanted fingers imply that intact sympathetic nerve function is required to induce the vasoconstrictive effect of EMLA. Expand
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Free flow of sweat due to loss of surface tension at sweat droplets causes water-induced skin wrinkling
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Mechanics Reveals the Biological Trigger in Wrinkly Fingers
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It is concluded that, with the subject in a warm state, blood vessels of the finger respond to local heating with vasoconstriction, and this finger vasconstriction is evoked reflexively, largely through the increased sympathetic outflow to the resistance vessels ofThe finger. Expand
Skin wrinkling for the assessment of sympathetic function in the limbs.
The wrinkle test is a reliable test of sympathetic function, is inexpensive and is easy to perform at the bedside, and can adequately evaluate sympathetic blockade. Expand
Contribution of arteriovenous anastomoses to vasoconstriction induced by local heating of the human finger.
The results suggest that the decrease in finger blood flow in response to local heating may be limited to AVAs, and superficial vessels may not contribute to this heat-induced vasoconstriction of the finger. Expand
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Decreased Skin Wrinkling in Diabetes Mellitus
Markedly decreased skin wrinkling was observed in diabetic subjects and in manual workers, but did not correlate with cardiovascular tests of autonomic function, control, type or duration of diabetes, or diabetic complications. Expand
Skin wrinkling on immersion of hands: a test of sympathetic function.
Skin wrinkling of the fingers following immersion in warm water depends on intact sympathetic innervation and affords a simple and reliable clinical test of sympathetic function. Expand
Abnormal skin wrinkling in the less affected side in hemiparkinsonism-a possible test for sympathetic dysfunction in Parkinson's disease.
The skin wrinkling response following immersion of the hands in warm water in 18 patients with hemiparkinsonism is examined to suggest that autonomic dysfunction is prevalent in the less affected side of patients with PD and can be simply tested by the skin response test. Expand
The arteriovenous pattern of the distal digital segment.
By injection of eosin dye with latex into 45 cadaveric fingers we were able to demonstrate: (1) a distinct digital pulp arch formed by the ulnar and radial digital arteries over the mid-point of theExpand
New and Simple Test of Nerve Function in Hand
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The fine structure of human digital arterio-venous anastomoses (Hoyer-Grosser's organs)
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