Water, water, everywhere

  title={Water, water, everywhere},
  author={Benedikt Wiggli and Edelbert Imhof and Christoph A. Meier and Gerd Laifer},
  journal={The Lancet},
6 Citations

Generalised edema with human parvovirus B19 infection

The mild normocytic anaemia improved spontaneously and was determined to be due to a transient viral infection, B19V infection with generalised pitting oedema, which suggests a capillary leak syndromelike mechanism, but the aetiology remains to be elucidated.

Generalized edema associated with parvovirus B19 infection.

  • P. VlaarG. MithoeW. Janssen
  • Medicine
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 2014

Mechanism of Multi-Organ Injury in Experimental COVID-19 and Its Inhibition by a Small Molecule Peptide

The findings suggest the possible involvement of altered aquaporins and the subsequent edema, likely mediated by the virus-induced inflammatory and oxidative stress response, in the pathogenesis of COVID- 19 and the potential of SPIKENET as a therapeutic option.



Parvovirus infection and generalized edema in adults.

In all 7 patients, there was serological confirmation of recent HPV infection, and all showed the development of edema following HPV infection without urine abnormalities or anemia, and two patients showed signs of congestive heart failure.

Papular-purpuric gloves and socks syndrome associated with acute parvovirus B19 infection: case report and review.

The patient presented with the typical clinical syndrome, and the diagnosis of acute parvovirus B19 infection was documented by serial serologies that demonstrated development of IgM antibody to virus during the acute phase of infection and seroconversion to IgG antibody in the convalescent period.

Experimental Parvoviral Infection in Humans

The hematologic changes associated with infection support the hypothesis that the same virus is responsible for the temporary arrest of erythropoiesis that leads to aplastic crisis in persons with chronic hemolytic anemia.

Parvovirus-associated arthritis

  • T. Moore
  • Medicine
    Current opinion in rheumatology
  • 2000
The data indicate it is unlikely that B19 infection causes rheumatoid arthritis or systemic lupus erythematosus, but continued studies of the pathogenesis of acute and chronic parvoviral B19 infections and arthropathy may provide insights into virus–host interactions and mechanisms of joint disease and connective tissue disease.