Water, water, everywhere

  title={Water, water, everywhere},
  author={Benedikt J Wiggli and Edelbert Imhof and Christoph A. Meier and Gerd Laifer},
  journal={The Lancet},
In July, 2010, a previously healthy 34-year-old woman presented to us with fatigue and progressive generalised oedema. 3 weeks earlier, she had had faint exanthema on her arms and legs followed by transient swelling of the ankles, knees, and hands. Bilateral oedema of the legs with progression to the trunk and the arms, periorbital oedema, shortness of breath, and weight gain of 10 kg within 1 week led to hospital admission. On examination, her vital signs were normal. Pronounced pitting oedema… Expand
5 Citations
Generalised edema with human parvovirus B19 infection
The mild normocytic anaemia improved spontaneously and was determined to be due to a transient viral infection, B19V infection with generalised pitting oedema, which suggests a capillary leak syndromelike mechanism, but the aetiology remains to be elucidated. Expand
Generalized edema associated with parvovirus B19 infection.
  • P. Vlaar, G. Mithoe, W. Janssen
  • Medicine
  • International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 2014
The case of a young adult presenting with generalized edema with serological and PCR evidence of parvovirus B19 infection is reported, and the potential mechanisms of edema are discussed based on the previous literature. Expand
[Facial edema in a 39-year-old woman].
Une femme, âgée de 39 ans, sans antécédent médical notable si e n’est une chirurgie de réduction mammaire à l’âge de 20 ans et ne opération des ligaments du genou consultait pour un œdème u visage.Expand
Cost Avoidance and Outcome Improvement by Implementing a Test Utilization Strategy for Molecular Microbiology Tests
A triage system for molecular microbiology tests ordered from 2007 through 2010 to assess their appropriateness before they were sent out to a reference laboratory for testing to avoid unnecessary cost and improve patient care was designed. Expand


Parvovirus infection and generalized edema in adults.
In all 7 patients, there was serological confirmation of recent HPV infection, and all showed the development of edema following HPV infection without urine abnormalities or anemia, and two patients showed signs of congestive heart failure. Expand
Papular-purpuric gloves and socks syndrome associated with acute parvovirus B19 infection: case report and review.
The patient presented with the typical clinical syndrome, and the diagnosis of acute parvovirus B19 infection was documented by serial serologies that demonstrated development of IgM antibody to virus during the acute phase of infection and seroconversion to IgG antibody in the convalescent period. Expand
Experimental Parvoviral Infection in Humans
The hematologic changes associated with infection support the hypothesis that the same virus is responsible for the temporary arrest of erythropoiesis that leads to aplastic crisis in persons with chronic hemolytic anemia. Expand
Parvovirus-associated arthritis
  • T. Moore
  • Medicine
  • Current opinion in rheumatology
  • 2000
The data indicate it is unlikely that B19 infection causes rheumatoid arthritis or systemic lupus erythematosus, but continued studies of the pathogenesis of acute and chronic parvoviral B19 infections and arthropathy may provide insights into virus–host interactions and mechanisms of joint disease and connective tissue disease. Expand