Watchful waiting for small renal masses

@article{Mattar2008WatchfulWF,
  title={Watchful waiting for small renal masses},
  author={Kamal Mattar and Michael A. S. Jewett},
  journal={Current Urology Reports},
  year={2008},
  volume={9},
  pages={22-25}
}
Small renal masses (SRMs; < 4 cm in diameter) account for most renal tumors treated today. Incidental early detection of SRMs by abdominal imaging results in favorable grade and stage migration to renal cell carcinoma, and also increases detection of benign renal tumors. As a result, most SRMs manifest indolent biological behavior with excellent prognosis. Despite the increased use of minimally invasive laparoscopic surgery, nephron-sparing techniques, and percutaneous ablation therapy… 
Growth pattern of renal cell carcinoma (RCC) in patients with delayed surgical intervention
TLDR
RCCs were found to be slow growing in a group of untreated renal cell carcinoma patients, however, some tumors progressed in stage under observation, and the growth rate of RCC tended to correlate with histologic grade and histologic subtype.
Percutaneous ablation in the kidney.
TLDR
Clinical studies to date indicate that radiofrequency ablation and cryoablation are effective therapies with acceptable short- to intermediate-term outcomes and with a low risk in the appropriate setting, with attention to pre-, peri-, and postprocedural detail.
Image-Guided Radio Frequency Ablation of Renal Cancer 46
TLDR
This chapter looks at the suitability of renal tumors to percutaneous ablation, radiofrequency ablation equipment, and ablation techniques including imaging, patient sedation, and follow-up regimes.
Vigilancia activa en masas renales menores de 4 cm
Of all the malignant tumors, 3.5% correspond to renal cell carcinoma and its mortality rate is near 40%. The overall survival rate for localized renal tumors is of 90% at 5 years and 82% at 10 years
Incidental detection of synchronous primary tumours during staging workup for prostate cancer.
TLDR
In patients with prostate cancer, abdominopelvic CT staging detects incidental second primary cancers with a greater frequency than that expected.
Diagnostic accuracy and clinical impact of imaging-guided needle biopsy of renal masses. Retrospective analysis on 150 cases
TLDR
CB is more accurate than FNAB and should be preferred in renal mass biopsy and may precede CB when an expert pathologist can immediately evaluate the samples.
Integrated Molecular Analysis for the Identification and Validation of Novel Biomarkers for Renal Cell Carcinoma and the Small Renal Mass
TLDR
An integrated label-free LC-MS/MS proteomics and peptidomics approach and targeted parallel-reaction monitoring (PRM) to identify early non-invasive biomarkers of RCC progression are developed and qRT-PCR is performed to identify prognostic (predict early R CC progression) and diagnostic (RCC subtype classification) miRNAs.
Renal cell carcinoma: stage, grade and histology migration over the last 15 years in a large Australian surgical series
Study Type – Therapy (case series) 
Level of Evidence 4
...
...

References

SHOWING 1-10 OF 43 REFERENCES
Nephron-sparing surgery for renal cell carcinoma.
Rising Incidence of Small Renal Masses: A Need to Reassess Treatment Effect
TLDR
The results demonstrate that the rising incidence of kidney cancer is largely attributable to an increase in small renal masses that are presumably curable, and argues for a reassessment of the current treatment paradigm.
Increased incidence of serendipitously discovered renal cell carcinoma.
Prognostic importance of tumor size for localized conventional (clear cell) renal cell carcinoma
TLDR
This study investigates the prognostic significance of tumor size in a series of organ‐confined clear cell renal cell carcinomas to identify patients suitable for partial nephrectomy.
...
...