Wastewater Testing and Detection of Poliovirus Type 2 Genetically Linked to Virus Isolated from a Paralytic Polio Case — New York, March 9–October 11, 2022

@article{Ryerson2022WastewaterTA,
  title={Wastewater Testing and Detection of Poliovirus Type 2 Genetically Linked to Virus Isolated from a Paralytic Polio Case — New York, March 9–October 11, 2022},
  author={A. Blythe Ryerson and Daniel Lang and Mohammed A. Alazawi and Milagros Neyra and Dustin T. Hill and Kirsten St. George and Meghan E. Fuschino and Emily C. Lutterloh and Bryon P. Backenson and Samuel J. Rulli and Patricia Schnabel Ruppert and Jacqueline Lawler and Nancy A. McGraw and Andrew Knecht and Irina Gelman and Jane R. Zucker and Enoma Omoregie and Sarah Kidd and David Sugerman and Jaume Jorba and Nancy Gerloff and Terry Fei Fan Ng and Adriana Isabel Henao L{\'o}pez and Nina B. Masters and Jessica W Leung and Cara C. Burns and Janell A. Routh and Stephanie R. Bialek and M. Steven Oberste and Eli S. Rosenberg and Bridget J. Anderson and Noelle Anderson and Jed A. Augustine and Megan Baldwin and Kelly M. Schiabor Barrett and Ursula E. Bauer and Andrew Beck and Hanen Belgasmi and Lydia J. Bennett and Achal Bhatt and Debra S. Blog and Heather Boss and Isaac Ravi Brenner and Barrett Brister and Travis Wayne Brown and Tavora Buchman and James Bullows and Kara Connelly and Blaise Cassano and Christina J. Castro and Cynthia Cirillo and George Edward Cone and Janine Cory and Amina Dasin and Adina de Coteau and Anny DeSimone and F Chauvin and Cynthia Dixey and Kathleen L. Dooling and S. Jeffery Scottsdale Doss and Christopher R. Duggar and Christopher N. Dunham and Delia E. Easton and Christina T. Egan and Brian D. Emery and Randall English and Nicola Faraci and Hannah E. Fast and G. Stephanie Feumba and Nancy L. Fischer and Stephen Flores and Ann D. Frolov and Halle Getachew and Brittany Gianetti and Alejandro Padr{\'o}n God{\'i}nez and Todd A. Gray and William R. Gregg and Christina Gulotta and Sarah T. Hamid and Tiffany Hammette and Rafael Harpaz and Liam Smith and Brianna Hanson and Elizabeth Henderson and Eugene Heslin and Alexandra Hess and Dina Hoefer and Jonathan Hoffman and Lyndsey Hoyt and Scott Hughes and Anna R. Hutcheson and Tabassum Z. Insaf and Christopher Ionta and Stacey Jeffries Miles and Anita K. Kambhampati and Haley R. Kappus-Kron and Genevieve N. Keys and Michael Kharfen and Gimin Kim and Jenna Tracy Knox and Stephanie D. Kovacs and Julie Krauchuk and Elisabeth R. Krow-Lucal and Daryl M. Lamson and Jennifer Laplante and David A. Larsen and Ruth Link-Gelles and Hongmei Liu and James Lueken and Kevin Ma and Rachel L. Marine and Karen A. Mason and James McDonald and Kathleen A. McDonough and Kevin T McKay and Eva D. McLanahan and Eric Medina and Haillie C. Meek and Gul M Mustafa and Megan D Meldrum and Elizabeth Mello and Jeffrey W Mercante and Mandar Mhatre and Susan Gilson Miller and Natalie Migliore and Neida K. Mita-Mendoza and Amruta Moghe and Nehalraza Momin and Tanner Morales and E. Joe Moran and Grace Nabakooza and Dana Neigel and Simon Ogbamikael and Jason O’Mara and Stephanie E. Ostrowski and Manisha Patel and Prabasaj Paul and Atefeh Paziraei and Georgina Peacock and Lauren Pearson and Jonathan Plitnick and Alicia Pointer and Michael D Popowich and Chitra Punjabi and Rama Ramani and Shailla J. Raymond and Lindsey Rickerman and Erik Rist and Angela Robertson and Shannon L. Rogers and Jennifer B. Rosen and Cecelia A. Sanders and Jeanne M. Santoli and Leanna Sayyad and Lynsey Schoultz and Matthew Shudt and Justin Smith and Theresa L. Smith and Maria Souto and Ashleigh Staine and Shannon K. Stokley and Hong Sun and Andrew J. Terranella and Ashley Tippins and F A Tobolowsky and Megan Wallace and Steven G. F. Wassilak and Amanda Wolfe and Eileen L Yee},
  journal={Morbidity and Mortality Weekly Report},
  year={2022},
  volume={71},
  pages={1418 - 1424}
}
In July 2022, a case of paralytic poliomyelitis resulting from infection with vaccine-derived poliovirus (VDPV) type 2 (VDPV2)§ was confirmed in an unvaccinated adult resident of Rockland County, New York (1). As of August 10, 2022, poliovirus type 2 (PV2)¶ genetically linked to this VDPV2 had been detected in wastewater** in Rockland County and neighboring Orange County (1). This report describes the results of additional poliovirus testing of wastewater samples collected during March 9… 
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References

SHOWING 1-10 OF 15 REFERENCES

Public Health Response to a Case of Paralytic Poliomyelitis in an Unvaccinated Person and Detection of Poliovirus in Wastewater — New York, June–August 2022

The occurrence of this case, combined with the identification of poliovirus in wastewater in neighboring Orange County, underscores the importance of maintaining high vaccination coverage to prevent paralytic polio in persons of all ages.

Diagnostic Assay Development for Poliovirus Eradication

Two new assays targeting recently circulating WPV1 genotypes and all PV2 viruses are designed and pilot tested, and the creation and properties of quantitation standards, including 16 control RNA transcripts and nine plaque-isolated viruses are described.

CaFÉ: A Sensitive, Low-Cost Filtration Method for Detecting Polioviruses and Other Enteroviruses in Residual Waters

The results of 338 parallel-tested samples show that the CAFÉ method is more sensitive than the two-phase separation method for detection of non-polio enteroviruses (p-value < 0.0001) and performed as well as the two -phase separation methods for polioviruses detection with no significant difference ( p-value > 0.05).

Validation of a redesigned pan-poliovirus assay and real-time PCR platforms for the global poliovirus laboratory network

validation of performance of real-time PCR platforms is a core requirement for the detection of poliovirus using the ITD kit and the updated PanPV probe performance was shown to reduce background fluorescence and decrease the number of false positives compared to the standard PanPv probe.

Serologic response to oral polio vaccine and enhanced-potency inactivated polio vaccines.

The third dose of inactivated polio vaccine produced significant increases in the reciprocal geometricmean titers against each of the three poliovirus types and resulted in significantly higher reciprocal geometric mean titers after three doses of vaccine for recipients of inactivation polio vaccine than for recipientsof oral polio vaccine.

Poliomyelitis prevention in the United States. Updated recommendations of the Advisory Committee on Immunization Practices (ACIP).

The Advisory Committee on Immunization Practices (ACIP) reaffirms its support for the global polio eradication initiative and the use of OPV as the only vaccine recommended to eradicate polio from the remaining countries where polio is endemic.

Vaccination Coverage by Age 24 Months Among Children Born in 2017 and 2018 — National Immunization Survey-Child, United States, 2018–2020

Extra efforts are needed to ensure that children who missed vaccinations, including those attributable to the COVID-19 pandemic, receive them as soon as possible to maintain protection against vaccine-preventable illnesses.

Vaccination Coverage by Age 24 Months Among Children Born in 2015 and 2016 — National Immunization Survey-Child, United States, 2016–2018

Assessment of vaccination coverage with the recommended number of doses of each vaccine at the national, state, territorial, and selected local levels among children born in 2015 and 2016 found that coverage was lower for uninsured children and for children insured by Medicaid than for those with private health insurance.

Updated recommendations of the Advisory Committee on Immunization Practices (ACIP) regarding routine poliovirus vaccination.

  • Medicine
    MMWR. Morbidity and mortality weekly report
  • 2009
This report updates Advisory Committee on Immunization Practices (ACIP) recommendations for routine poliovirus vaccination. These updates aim to 1) emphasize the importance of the booster dose at age

Using geographic information systems to link population estimates to wastewater surveillance data in New York State, USA

Sewer systems provide many services to communities that have access to them beyond removal of waste and wastewater. Understanding of these systems geographic coverage is essential for