Warm vs. cold perfusion techniques to rescue rodent liver grafts.

@article{Schlegel2014WarmVC,
  title={Warm vs. cold perfusion techniques to rescue rodent liver grafts.},
  author={Andrea Anja Schlegel and Philipp Kron and Rolf E. Graf and Philipp Dutkowski and Pierre Alain Clavien},
  journal={Journal of hepatology},
  year={2014},
  volume={61 6},
  pages={
          1267-75
        }
}
BACKGROUND & AIMS A variety of liver perfusion techniques have been proposed to protect liver grafts prior to implantation. We compared hypothermic and normothermic oxygenated perfusion techniques in a rat liver transplant model, using higher risk grafts obtained after cardiac arrest (DCD). METHODS Rat livers were subjected to 30 or 60 min in situ warm ischemia, without application of heparin. Livers were excised and stored for 4 h at 4°C, mimicking DCD organ procurement, followed by… CONTINUE READING
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