Warkmycin, a novel angucycline antibiotic produced by Streptomyces sp. Acta 2930*

@article{Helaly2013WarkmycinAN,
  title={Warkmycin, a novel angucycline antibiotic produced by Streptomyces sp. Acta 2930*},
  author={Soleiman E. Helaly and Michael J. Goodfellow and Heidi Zinecker and Johannes F Imhoff and Roderich D S{\"u}ssmuth and H. -P. Fiedler},
  journal={The Journal of Antibiotics},
  year={2013},
  volume={66},
  pages={669-674}
}
A novel angucycline-type antibiotic, warkmycin, was isolated from the culture filtrate of Streptomyces strain Acta 2930. Its chemical structure was elucidated by HR-MS, one-dimensional and 2D NMR experiments. The compound inhibits the growth of Gram-positive bacteria and shows a strong antiproliferative activity against mouse fibroblast cell line NIH-3T3 and human cancer cell lines HepG2 and HT29. 
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