Warfarin dosing algorithm using clinical, demographic and pharmacogenetic data from Chinese patients

@article{You2010WarfarinDA,
  title={Warfarin dosing algorithm using clinical, demographic and pharmacogenetic data from Chinese patients},
  author={Joyce H S You and Raymond S M Wong and Mary Miu Yee Waye and Yawei Mu and Cadmon K. Lim and Kai Chow Choi and Gregory Cheng},
  journal={Journal of Thrombosis and Thrombolysis},
  year={2010},
  volume={31},
  pages={113-118}
}
CYP2C9 and VKORC1 genotypes could be used to predict warfarin requirement. The objective was to develop and validate a warfarin dosing algorithm using genetic, clinical and demographic data of Chinese patients from an anticoagulation clinic in Hong Kong. Blood samples were collected from 100 patients on stable maintenance dose of warfarin, recruited from an anticoagulation clinic, for genotyping CYP2C9 and VKORC1. Clinical and demographic data were obtained by face-to-face interview and medical… CONTINUE READING