Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers’ most common phenotypes, the “Warburg Effect”, i.e., elevated glycolysis in the presence of oxygen

@article{Pedersen2007WarburgMA,
  title={Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers’ most common phenotypes, the “Warburg Effect”, i.e., elevated glycolysis in the presence of oxygen},
  author={P. Pedersen},
  journal={Journal of Bioenergetics and Biomembranes},
  year={2007},
  volume={39},
  pages={211-222}
}
  • P. Pedersen
  • Published 2007
  • Biology, Medicine
  • Journal of Bioenergetics and Biomembranes
  • As a new faculty member at The Johns Hopkins University, School of Medicine, the author began research on cancer in 1969 because this frequently fatal disease touched many whom he knew. He was intrigued with its viscous nature, the failure of all who studied it to find a cure, and also fascinated by the pioneering work of Otto Warburg, a biochemical legend and Nobel laureate. Warburg who died 1 year later in 1970 had shown in the 1920s that the most striking biochemical phenotype of cancers is… CONTINUE READING
    387 Citations
    Oxidative Phosphorylation and Cancer: The Ongoing Warburg Hypothesis
    • 9
    Warburg Effect - a Consequence or the Cause of Carcinogenesis?
    • S. Devic
    • Biology, Medicine
    • Journal of Cancer
    • 2016
    • 65
    • PDF
    The Warburg effect: insights from the past decade.
    • 168
    Molecular intricacies of aerobic glycolysis in cancer: current insights into the classic metabolic phenotype
    • 37
    Manipulation of glycolysis in malignant tumors: fantasy or therapy?
    • 30

    References

    SHOWING 1-10 OF 69 REFERENCES
    Tumor metabolism: new opportunities for cancer therapy
    • I. Mérida, A. Ávila-Flores
    • Biology, Medicine
    • Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
    • 2006
    • 33
    Mitochondria and cancer: Warburg addressed.
    • D. Wallace
    • Chemistry, Medicine
    • Cold Spring Harbor symposia on quantitative biology
    • 2005
    • 255
    • PDF
    Glucose Catabolism in Cancer Cells
    • 345
    • PDF
    Glucose Catabolism in Cancer Cells.
    • 141
    • PDF
    Oxidative metabolism in cancer growth
    • M. Ristow
    • Biology, Medicine
    • Current opinion in clinical nutrition and metabolic care
    • 2006
    • 127
    Mitochondrial Hexokinases: Guardians of the Mitochondria
    • 99
    Glucose Metabolism in Cancer
    • 110
    • PDF