Waon Therapy for Managing Chronic Heart Failure - Results From a Multicenter Prospective Randomized WAON-CHF Study.

@article{Tei2016WaonTF,
  title={Waon Therapy for Managing Chronic Heart Failure - Results From a Multicenter Prospective Randomized WAON-CHF Study.},
  author={Chuwa Tei and Teruhiko Imamura and Koichiro Kinugawa and Teruo Inoue and Tohru Masuyama and Hiroshi Inoue and Hirofumi Noike and Toshihiro Muramatsu and Yasuchika Takeishi and Keijiro Saku and Kazumasa Harada and Hiroyuki Daida and Youichi Kobayashi and Nobuhisa Hagiwara and Masatoshi Nagayama and Shinichi Momomura and Kazuya Yonezawa and Hiroshi Ito and Satoshi Gojo and Makoto Akaishi and Masaaki Miyata and Mitsuru Ohishi},
  journal={Circulation journal : official journal of the Japanese Circulation Society},
  year={2016},
  volume={80 4},
  pages={827-34}
}
BACKGROUND Waon therapy improves heart failure (HF) symptoms, but further evidence in patients with advanced HF remains uncertain. METHODSANDRESULTS In 19 institutes, we prospectively enrolled hospitalized patients with advanced HF, who had plasma levels of B-type natriuretic peptide (BNP) >500 pg/ml on admission and BNP >300 pg/ml regardless of more than 1 week of medical therapy. Enrolled patients were randomized into Waon therapy or control groups. Waon therapy was performed once daily for… CONTINUE READING
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