Corpus ID: 1491927

Walnut-enriched diet increases the association of LDL from hypercholesterolemic men with human HepG2 cells.

@article{Muoz2001WalnutenrichedDI,
  title={Walnut-enriched diet increases the association of LDL from hypercholesterolemic men with human HepG2 cells.},
  author={S Mu{\~n}oz and Manuel Merlos and Daniel Zamb{\'o}n and Cristina Rodr{\'i}guez and Joan Sabat{\'e} and Emilio Ros and Juan Carlos Laguna},
  journal={Journal of lipid research},
  year={2001},
  volume={42 12},
  pages={
          2069-76
        }
}
In a randomized, cross-over feeding trial involving 10 men with polygenic hypercholesterolemia, a control, Mediterranean-type cholesterol-lowering diet, and a diet of similar composition in which walnuts replaced approximately 35% of energy from unsaturated fat, were given for 6 weeks each. Compared with the control diet, the walnut diet reduced serum total and LDL cholesterol by 4.2% (P = 0.176), and 6.0% (P = 0.087), respectively. No changes were observed in HDL cholesterol, triglycerides… Expand
Effects of Walnuts on Serum Cholesterol Levels in People with Normo- or Hyperlipidemia
TLDR
The studies conclude that walnut consumption may help reduce risk of heart disease and more studies using larger sample sizes and clearer standards for accurately attributing properties to walnuts should be conducted to provide a better understanding of the role of walnuts. Expand
A Walnut Diet Improves Endothelial Function in Hypercholesterolemic Subjects: A Randomized Crossover Trial
TLDR
Substituting walnuts for monounsaturated fat in a Mediterranean diet improves endothelium-dependent vasodilation in hypercholesterolemic subjects, and this finding might explain the cardioprotective effect of nut intake beyond cholesterol lowering. Expand
Reduction in systemic and VLDL triacylglycerol concentration after a 3-month Mediterranean-style diet in high-cardiovascular-risk subjects.
TLDR
The VLDL composition in 50 participants after 3 months of intake of two MD, supplemented with VOO or nuts, compared with a low-fat diet was assessed and it was concluded that the reduction in systemic TG concentrations observed after consumption of the MD may be explained by reduction of the lipid core of V LDL and a selective modification of the molecular species composition in the particle. Expand
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TLDR
There are persuasive evidences that dietary substitution of monounsaturated fatty acids (MUFA) or n-6 polyunsaturated fatty acid (PUFA) for SFA lowers blood cholesterol and may have beneficial effects on inflammation, thrombosis, and vascular reactivity. Expand
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TLDR
Daily consumption of 43g of walnuts for 8weeks significantly reduced non-HDL-cholesterol and apolipoprotein-B, which may explain in part the epidemiological observation that regular walnut consumption decreases CHD risk. Expand
Pistachio Nut Consumption and Serum Lipid Levels
TLDR
A diet consisting of 15% of calories as pistachio nuts (about 2–3 ounces per day) over a four week period can favorably improve some lipid profiles in subjects with moderate hypercholesterolemia and may reduce risk of coronary disease. Expand
Effect of Walnut Consumption on Serum Lipid Profiles, High-Sensitivity C-Reactive Protein and Nitric Oxide in Patients With Coronary Artery Disease
TLDR
The walnut consumption did not affect cholesterol levels in patients with CAD; however, it might be administered as an agent for reducing the cholesterol, which is one of the risk factors associated with CAD. Expand
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TLDR
The results undoubtedly indicated that walnuts should be an important part of nutrition for cardiovascular patients and subjects at high risks of cardiovascular disease development, especially subjects with hypercholesteremia. Expand
HDL Cholesterol Levels in Children with Mild Hypercholesterolemia: Effect of Consuming Skim Milk Enriched with Olive Oil and Modulation by the TAQ 1B Polymorphism in the CETP Gene
TLDR
The consumption of skim milk enriched with olive oil increases the HDL cholesterol and apolipoprotein A-I levels in children with hypercholesterolemia, this effect being more intense in carriers of the B1B1 genotype. Expand
Effects of walnut oil on lipid profiles in hyperlipidemic type 2 diabetic patients: a randomized, double-blind, placebo-controlled trial
TLDR
Addition of walnut oil in the daily diet of type 2 diabetic patients improves lipid profiles, and it may be associated with a coronary artery disease risk factor modulation. Expand
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TLDR
A dietary intervention study in free-living adult men and women with polygenic hypercholesterolemia to compare the effects of a walnut-rich diet with those of a cholesterol-lowering Mediterranean diet on serum lipid levels, lipoprotein levels, and LDL resistance to oxidation is designed. Expand
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BACKGROUND In a recent six-year follow-up study, we found that frequent consumption of nuts was associated with a reduced risk of ischemic heart disease. To explore possible explanations for thisExpand
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TLDR
Moderate supplementation with fish oil n-3 fatty acids in normal humans enriches their LDL particles in cholesteryl esters and n- 3 fatty acids, which depress both LDL receptor activity and LDL receptor mRNA abundance in HepG2 cells. Expand
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