Wallerian degeneration and inflammation in rat peripheral nerve detected by in vivo MR imaging.

  title={Wallerian degeneration and inflammation in rat peripheral nerve detected by in vivo MR imaging.},
  author={David S Titelbaum and James L. Frazier and Robert I. Grossman and Peter Mwita Joseph and Larry T. H. Yu and E A Kassab and William F. Hickey and Don Larossa and Mark D. J. Brown},
  journal={AJNR. American journal of neuroradiology},
  volume={10 4},
To investigate the role of MR imaging in wallerian degeneration, a series of animal models of increasingly complex peripheral nerve injury were studied by in vivo MR. Proximal tibial nerves in brown Norway rats were either crushed, transected (neurotomy), or transected and grafted with Lewis rat (allograft) or brown Norway (isograft) donor nerves. The nerves distal to the site of injury were imaged at intervals of 0-54 days after surgery. Subsequent histologic analysis was obtained and… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 15 extracted citations


Publications referenced by this paper.
Showing 1-10 of 16 references

Pathologic alterations of the peripheral nervous system of humans

  • PJ Dyck, J Karnes, A Lais, EP Lofgren, JC. Stevens
  • Peripheral neuropathy,
  • 1984
Highly Influential
4 Excerpts

Cell interactions studied in the peripheral nerves of experimental animals

  • AJ Aguayo, GM Bray
  • Peripheral neuropathy,
  • 1984
2 Excerpts

Experimental study of nerve allografts : especially on the influence of histocompatibility in fresh nerve grafting

  • Y Hirasawa, K Tarnai, Y Katsumi, K Sakakida
  • Transplant Proc
  • 1984

Water compartments in the myelinated nerve . Ill . Pulsed NMR results

  • V Vasilescu, E Katona, V Simplaceanu, D Demeo
  • Experimentia
  • 1978

Similar Papers

Loading similar papers…