Waldenström's macroglobulinemia: long-term results with the M-2 protocol.

  title={Waldenstr{\"o}m's macroglobulinemia: long-term results with the M-2 protocol.},
  author={Delvyn C. Case and Thomas J. Ervin and Mary Ann Boyd and D L Redfield},
  journal={Cancer investigation},
  volume={9 1},
Thirty-three patients with symptomatic Waldenström's macroglobulinemia have been treated with the M-2 protocol (BCNU, cyclophosphamide, vincristine, melphalan, and prednisone). Therapy was administered every 5 weeks for 2 years and every 10 weeks for an additional 1-3 years. Median clinical and laboratory parameters included age 70 years (range 52-87), performance status 1 (1-3), prior therapy 7, weight loss 12, symptomatic hyperviscosity 13, splenomegaly 22, lymphadenopathy 7, hemoglobin 9.6 g… CONTINUE READING


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