Waldenström's macroglobulinemia: hyperviscosity syndrome and cryoglobulinemia.

  title={Waldenstr{\"o}m's macroglobulinemia: hyperviscosity syndrome and cryoglobulinemia.},
  author={Marvin J. Stone},
  journal={Clinical lymphoma & myeloma},
  volume={9 1},
Hyperviscosity syndrome (HVS) is a common manifestation of Waldenström's macroglobulinemia (WM). Patients with HVS have skin and mucosal bleeding, retinopathy with visual disturbances, and a variety of neurologic disorders. HVS can be diagnosed from physical examination by identifying the characteristic retinal venous engorgement ("sausaging") on funduscopic inspection. HVS can be accurately monitored with an Ostwald tube and reversed by plasmapheresis. Cryoglobulins precipitate or gel at… CONTINUE READING


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