Waldenstróm's macroglobulinemia with peripheral neuropathy--the role of IgM M-protein in autoimmune mechanism.

@article{Wang1988WaldenstrmsMW,
  title={Waldenstr{\'o}m's macroglobulinemia with peripheral neuropathy--the role of IgM M-protein in autoimmune mechanism.},
  author={C R Wang and H C Chiu and Hung Chang Hsieh and Rebecca Hsieh and Y. Chen M. Wu and Chih Yuan Chuang},
  journal={Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology},
  year={1988},
  volume={21 1},
  pages={9-15}
}
A total of 11 cases of Waldenstróm's Macroglobulinemia (WM) have been investigated to study the association of the disease with neuropathy. A 53-year-old female patient (Wu) had a pronounced peripheral neuropathy, in which the role of IgM M-protein could be observed. Sections of Wu's biopsied sural nerve were subjected to light and electron microscopy and direct immunofluorescence (IF). Myelin degeneration with axonal change was found, while fluorescence reaction occurred in epineurium only… CONTINUE READING

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