Wake-up or unclear-onset strokes: are they waking up to the world of thrombolysis therapy?

@article{Kang2012WakeupOU,
  title={Wake-up or unclear-onset strokes: are they waking up to the world of thrombolysis therapy?},
  author={Dong-Wha Kang and Joo Young Kwon and S. U. Kwon and Jong Sung Kim},
  journal={International journal of stroke : official journal of the International Stroke Society},
  year={2012},
  volume={7 4},
  pages={311-20}
}
Wake-up or unclear-onset strokes occur in up to one-fourth of patients with ischemic stroke. Although stroke severity and clinical outcomes appear to be poorer in wake-up strokes than nonwake-up strokes, many patients with wake-up strokes do not receive thrombolytic therapy because stroke onset time cannot be determined. Recent studies have suggested, however, that the actual onset time of wake-up stroke is close to the wake-up time. Furthermore, advanced imaging technologies may enable us to… CONTINUE READING