Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action.

Abstract

The hypocretins (orexins) are a newly identified peptide family comprised of two peptides, hypocretin-1 and hypocretin-2. Recent observations suggest an involvement of these peptides in the regulation of behavioral state. For example, these peptides are found in a variety of brain regions associated with the regulation of forebrain neuronal and behavioral… (More)

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