WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia.

@article{Inoue1994WT1AA,
  title={WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia.},
  author={Keiji Inoue and Haruo Sugiyama and Hiroyasu Ogawa and Masao Nakagawa and Tomohide Yamagami and Hiroshi Miwa and Kengo Kita and Akira Hiraoka and Toru Masaoka and Kimio Nasu},
  journal={Blood},
  year={1994},
  volume={84 9},
  pages={3071-9}
}
The WT1 gene encoding a zinc finger polypeptide is a tumor suppressor gene that plays a key role in the carcinogenesis of Wilms' tumor. Reverse transcriptase-polymerase chain reaction (RT-PCR) was used to examine relative levels of WT1 gene expression (defined in K562 cells as 1.00) in 45 patients with acute myelogenous leukemia (AML), 22 with acute lymphocytic leukemia (ALL), 6 with acute mixed lineage leukemia (AMLL), 23 with chronic myelogenous leukemia (CML), and 24 with non-Hodgkin's… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 229 extracted citations

Prognostic significance of wilms tumor 1 gene in childhood acute Lymphoblastic Leukemia.

Turkish journal of haematology : official journal of Turkish Society of Haematology • 2000
View 6 Excerpts
Highly Influenced

Clinical Impact of Overexpression of FOXP3 and WT1 on Disease Outcome in Egyptian Acute Myeloid Leukemia Patients

Asian Pacific journal of cancer prevention : APJCP • 2016
View 2 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…