WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis.

@article{Vuga2009WNT5AIA,
  title={WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis.},
  author={Louis J. Vuga and Ahmi Ben-Yehudah and Elizabetha Kovkarova-Naumovski and Timothy Oriss and Kevin F. Gibson and Carol Feghali-Bostwick and Naftali Kaminski},
  journal={American journal of respiratory cell and molecular biology},
  year={2009},
  volume={41 5},
  pages={
          583-9
        }
}
Usual interstitial pneumonia (UIP) is a specific histopathologic pattern of interstitial lung fibrosis that may be idiopathic or secondary to autoimmune diseases and environmental exposures. In this study, we compared gene expression patterns in primary fibroblasts isolated from lung tissues with UIP histology and fibroblasts isolated from lung tissues with normal histology using expression microarrays. We found that WNT5A was significantly increased in fibroblasts obtained from UIP lung… CONTINUE READING
Highly Cited
This paper has 84 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 48 extracted citations

Expression of WNT5A in Idiopathic Pulmonary Fibrosis and Its Control by TGF-β and WNT7B in Human Lung Fibroblasts.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society • 2016
View 5 Excerpts
Method Support
Highly Influenced

Wnt5a is elevated in heart failure and affects cardiac fibroblast function

Journal of Molecular Medicine • 2017
View 4 Excerpts
Highly Influenced

WNT-5A: signaling and functions in health and disease

Cellular and Molecular Life Sciences • 2015
View 4 Excerpts
Highly Influenced

An ex vivo model to induce early fibrosis-like changes in human precision-cut lung slices.

American journal of physiology. Lung cellular and molecular physiology • 2017
View 1 Excerpt

85 Citations

01020'11'13'15'17'19
Citations per Year
Semantic Scholar estimates that this publication has 85 citations based on the available data.

See our FAQ for additional information.