WNT Signaling in Cutaneous Squamous Cell Carcinoma: A Future Treatment Strategy?

The molecular mechanisms underlying cutaneous squamous cell carcinoma are less well established than those for other common skin cancers, but recent evidence has highlighted a potentially critical role for WNT signaling in both the development and progression of cutaneous squamous cell carcinoma. WNT pathways are aberrantly regulated in multiple tumor types… CONTINUE READING